Targeting partialy disordered proteins

Partially disordered proteins (PDPs) contain a mixture of stable and unstable secondary structure segments under physiological conditions though they have key roles in cell signaling and regulation.

Numerous PDPs are associated with a range human diseases, including cancer and cardiovascular diseases, still remaining undruggable.

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Elucidate order in the chaos

of partially disordered proteins

Integrating machine learning and physics based models , facilitates the structural characterization of partially disordered proteins , enabling efficient structure based drug discovery

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A new paradign in drug discovery

From structure based discovery to structural dynamics based drug discovery

Euclia's modeling capabillities and generative AI, generates optimized small molecule and biological agents targeting PDP's. From sequence to molecule in a matter of days.

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